6 Mar
2014
6 Mar
'14
12:16 p.m.
Dear all,
We would like to ask you to take a final look at the DecOCD proposal, which we would like
to submit tomorrow afternoon.
Please keep in mind that the proposal should be highly specific for the call PHC1.i
(copied below); in fact, the more we can use their exact wording, the better for us. For
instance, this call doesn't ask for biomarker identification (while others do), but
rather asks for risk determinant identification… Also remember that scientific excellence
and impact have equal weighting for the first round.
If possible, please make your changes directly to the doc in the dropbox (with change
tracking). I will deal with any/all conflicted copies. If you prefer to work offline,
I'm attaching a word doc that you can work on and then send back to Xavier and me.
We will incorporate all changes that we receive by tomorrow morning (13:00), after which
we will submit.
Thanks!
best wishes,
Veronica
Call wording: PHC1
Understanding health, ageing and disease
H2020-PHC-2014/2015
PHC 1 – 2014: Understanding health, ageing and disease: determinants, risk factors and
pathways
Specific challenge: The development and preservation of good health, and the occurrence
and evolution of common diseases and disabilities result from varying degrees of
interaction between the genetic make-up of individual human beings and behavioural,
environmental (including endocrine disruptors), occupational, nutritional and other
modifiable lifestyle factors. This applies from the earliest stages of development
throughout life.
Understanding these factors, their interactions and the extent to which they contribute to
health preservation and/or to disease development is important for the development of
preventive and therapeutic measures supporting good health, prolonged active independence
and a productive working life, not least in the context of changing demographic patterns
and the ageing of the European population. In particular, proposals should contribute to
improving risk identification and validation, and will allow better diagnosis, risk-based
prevention strategies and policies.
Scope:
i. The identification of health trends and determinants, their validation, and the
validation of risk factors for disease and disability, through the generation, integration
and validation of data derived from relevant disciplines (e.g. molecular, behavioural,
nutritional, clinical, social and environmental epidemiology; exposure sciences; genetics,
epigenetics, etc.). This should involve the exploitation of existing cohorts and
longitudinal studies and the assessment of the necessity to establish new ones, as well as
where relevant, the valorisation of knowledge gained from population-based bio-banks.
Sex and gender differences should be taken into account.
The Commission considers that proposals requesting a contribution from the EU of between
EUR 4 and 6 million would allow this specific challenge to be addressed appropriately.
Nonetheless, this does not preclude submission and selection of proposals requesting other
amounts.
Expected impact:
Proposals should provide a better understanding of the combined effects of factors causing
health and disease, with the knowledge generated underpinning the future development of
evidence based prevention, diagnostic, therapeutic and other strategies.
This should provide evidence for risk identification, underpinning future preventive,
diagnostic and therapeutic strategies and policies.