Hello,

Here are (belated) minutes of last Thursday's TC. The next call will be in November 22nd at 2pm CET.

- First, the most important point: The few remaining analysis results and methods text need to be sent to Tuuli without delay. The deadline was weeks ago, and now we can't wait any longer - I have already drafted the main paper.

- We got very good feedback at the Geuvadis annual meeting in Santiago de Compostela. A couple of important decisions regarding the RNAseq WP were made:
    - we decided to make a pre-publication data release of fastqs and bams, so the files are now out there, esiset access is through www.geuvadis.org. This was announced at the 1000 Genomes meeting, advertised in San Francisco in general, and now also mentioned in the 1000G website. The data is under embargo until publication of the main paper.
    - we discussed the author list - the latest version for the main paper can be seen under the data link. In addition to the ~60 named authors, there will be a "the Geuvadis consortium" listed before the PIs, and acknowledgements will include e.g. technicians. In the companions and subsequent papers, the people involved in that particular analyses should be named, and "the Geuvadis consortium" author will contain all the authors of the main paper, indexed and visible to PubMed.
    - people thought that making the wiki open to the public when the paper comes out is a good idea
    - there was discussion on future RNAseq experiments but no definite decisions on this

- At the ASHG meeting in SF people were in general very interested and impressed by our work. We discussed with editors of Nature and Science and both were interested in the paper; our first target will be Nature as discussed before. However, there is competition: a group from Stanford will be submitting a major RNAseq paper in the end of November, and while they don't have genome sequencing data and the analyses are not too badly overlapping, we really need to hurry up now so that their paper is not accepted before we submit.

- The main paper outline was discussed. Due to the competition situation, we need to submit by December 15, which is doable if we work hard. Tuuli has finished writing the first draft of the main paper text; this will be sent around soon. As mentioned above, any pending analyses need to be finished right now or they are very unlikely to make it to the paper. We are putting together the Supplement now but still missing methods text from 1-2 of you. Please send it to me without delay.

- We discussed the outline of the splicing paper. We should be able to submit that at the same time with the main paper.


best regards,
Tuuli



Tuuli Lappalainen, PhD
Department of Genetic Medicine and Development
University of Geneva Medical School
CMU / Rue Michel-Servet 1
1211 Geneva 4
Switzerland
Tel. +41-(0)22-3795550
tuuli.lappalainen@unige.ch
On /15/1112 5:54 AM, Tuuli Lappalainen wrote:
Hello all,

We'll have an RNAseq analysis group TC today at 2pm CET. Apologies for the late notice.

I hope many of you can attend since it's been a while due to me traveling; there are a number of important things to discuss:

- updates from Santiago de Chile
- updates from ASHG
- outline, timeline and action items for the main paper
- outlines, timelines and action items for the companion papers
- analysis updates
- AOB

Call details:
Germany         +49 692 573 804 41
Netherlands         +31 108 920 271
Spain         +34 931 816 661
Sweden         +46 840 309 949
Switzerland         +41 58 262 07 22
United Kingdom         +44 203 370 57 19
United States         +1 646 381 08 89
Access code: 611683

best,
Tuuli

-- 
Tuuli Lappalainen, PhD
Department of Genetic Medicine and Development
University of Geneva Medical School
CMU / Rue Michel-Servet 1
1211 Geneva 4
Switzerland
Tel. +41-(0)22-3795550
tuuli.lappalainen@unige.ch


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