Dear all,
We have revised the Geuvadis RNA-seq paper for Nature; please find
the paper and the response letter enclosed. If you have any
comments, please send them
by Saturday - apologies for the
tight schedule, we are planning to submit this on Monday. Thanks to
all of you who helped me with the revisions.
As many of you know, the editor adviced us to make the paper more
focused on the key messages, and as a consequence we had to drop
some of the analyses - fusion transcripts, soft splicing and RNA
editing. I hope that those results can be published in some other
context later on. To strengthen the analysis of regulatory variants,
I did some additional analysis on regulatory variants underlying
allele-specific expression signals, but otherwise the changes in the
paper are relatively small. I think that we were able to respond to
all the comments really well, and hopefully the editor and reviewers
agree.
best regards,
Tuuli
--
Tuuli Lappalainen, PhD
Department of Genetics, Stanford University School of Medicine , and
Department of Genetic Medicine and Development, University of Geneva
Email: tuuli.e.lappalainen@gmail.com / tlappala@stanford.edu
Tel: +1 415 351 9713
Bustamante lab
Department of Genetics
300 Pasteur Dr. Lane L301
Stanford, CA 94305-5120
USA