Dear all

We are all aware of the pitfalls of Pearson correlations on largely skewed data. Micha mentioned in Barcelona the OPS (optimal power space transformation package) that he developed. It worked very well to determine correlations between samples, I believe. Attached some results.

Best

Peter

Dr. Peter A.C. 't Hoen

Center for Human and Clinical Genetics

Leiden University Medical Center

Postal zone S4-P

PO Box 9600

2300 RC Leiden

The Netherlands

phone: +31-71-5269421

fax: +31-71-5268285

e-mail: p.a.c.hoen@lumc.nl