[Geuvadis_rnaseq] Geuvadis RNAseq and 1000 Genomes

Dear all, I would like to ask your opinion on potential collaboration in the future between the Geuvadis RNA sequencing project and the 1000 Genomes Consortium. There will be a 1000g project meeting in Montreal in mid-November that I will attend - me and Manolis belong to the 1000g analysis group. In the Phase 1 of the project there is now increasing interest to analyze functional consequences of the discovered variants, also in the regulatory context. There's no doubt that the Geuvadis dataset will be hugely valuable in annotating regulatory variation, which is of interest to many people. The vast majority of the work will naturally happen within the Geuvadis framework. However, the really unique property of our dataset is the combination of genome and transcriptome sequence data, and in my opinion the expertise that the 1000g people have in analyzing genome sequence might help us to get the most out of our data, benefiting us all. So, what would you think of exploring the possibilities for collaboration? We suggest that I will let relevant people from the 1000g consortium to know about Geuvadis, and discuss if there would be joint interests - open the door a little bit, so to say. It goes without saying all external collaborations would be conditional to full acceptance by the partners and all due credit to the Geuvadis project. Please let me know what you think by early October. best regards, Tuuli -- Tuuli Lappalainen, PhD Department of Genetic Medicine and Development University of Geneva Medical School CMU / Rue Michel-Servet 1 1211 Geneva 4 Switzerland Tel. +41-(0)22-3795550 tuuli.lappalainen(a)unige.ch