[Geuvadis_rnaseq] Geuvadis RNAseq and 1000 Genomes - geuvadis_rnaseq@lists.crg.es

27 Sep 2011

Dear all,

I would like to ask your opinion on potential collaboration in the 
future between the Geuvadis RNA sequencing project and the 1000 Genomes 
Consortium.

There will be a 1000g project meeting in Montreal in mid-November that I 
will attend - me and Manolis belong to the 1000g analysis group. In the 
Phase 1 of the project there is now increasing interest to analyze 
functional consequences of the discovered variants, also in the 
regulatory context.

There's no doubt that the Geuvadis dataset will be hugely valuable in 
annotating regulatory variation, which is of interest to many people. 
The vast majority of the work will naturally happen within the Geuvadis 
framework. However, the really unique property of our dataset is the 
combination of genome and transcriptome sequence data, and in my opinion 
the expertise that the 1000g people have in analyzing genome sequence 
might help us to get the most out of our data, benefiting us all.

So, what would you think of exploring the possibilities for 
collaboration? We suggest that I will let relevant people from the 1000g 
consortium to know about Geuvadis, and discuss if there would be joint 
interests - open the door a little bit, so to say. It goes without 
saying all external collaborations would be conditional to full 
acceptance by the partners and all due credit to the Geuvadis project.

Please let me know what you think by early October.

best regards,
Tuuli

-- 
Tuuli Lappalainen, PhD
Department of Genetic Medicine and Development
University of Geneva Medical School
CMU / Rue Michel-Servet 1
1211 Geneva 4
Switzerland
Tel. +41-(0)22-3795550
tuuli.lappalainen(a)unige.ch