[Geuvadis_rna_analysis] TC minutes

Hello, Here are some badly belated minutes from last week's analysis group TC. The next call will be this Thursday, October 11 at 2pm CET. - There's a new conference call system of a shared screen and notes that we can use later if we want to - Maarten presented some early results from miRNA-mRNA correlations. The background null distribution looks good and unbiased, and hopefully refining the analysis a bit further will help us to get a significant signal out of this. - Micha presented a draft plot for the paper of how gene discoveries increase as a function of sequenced samples - After the main call we had a splicing subgroup call - different splicing measures and splice scores of variants seem to correlate nicely, there's plenty of data and analysis is going well, although there's plenty of things to do especially wrapping up the sQTLs. - The next call will have a splicing theme: Micha will present splice junction analyses, and if there's time Tuuli will present allele-specific alternative splicing. For those who are interested, I've already updated the wiki with ASAS methods analyses (http://sanabre.net/geuvadis/index.php/Allele_specific_alternative_splicing). best, Tuuli -- Tuuli Lappalainen, PhD Department of Genetic Medicine and Development University of Geneva Medical School CMU / Rue Michel-Servet 1 1211 Geneva 4 Switzerland Tel. +41-(0)22-3795550 tuuli.lappalainen(a)unige.ch