Hello all,
I've uploaded normalized miRNA quantifications to the ftp site:
/upload/geuvadis/wp4_rnaseq/main_project/analysis_data/mirna/quantification_tables
. See wiki (
http://sanabre.net/geuvadis/index.php/Basic_methodology) for
details.
There are files for:
- 363 European QC-passed samples, corrected with 10 PEER factors
(including population and seqlab).
- 89 Yoruba QC-passed samples, corrected with 5 PEER factors (including
seqlab).
These files should be considered slightly preliminary - it is possible
that we'll end up using these in the end, but before freezing this I
want to do some covariate analysis (once I get the fastq QC stats).
We should do eQTL analysis separately for EUR and YRI, but as we
discussed on the call, miRNA-mRNA correlations could maybe be done on
the whole dataset after correcting for population. I'll produce these
files in ~1 week - for this I'll also need to normalize the mRNA data in
a similar manner, and that takes more time to run. In the meanwhile you
can probably use the population-specific data.
cheers,
Tuuli
--
Tuuli Lappalainen, PhD
Department of Genetic Medicine and Development
University of Geneva Medical School
CMU / Rue Michel-Servet 1
1211 Geneva 4
Switzerland
Tel. +41-(0)22-3795550
tuuli.lappalainen(a)unige.ch