Hello, At last I've finished running the allele-specific expression analysis for all the Geuvadis samples. The master file is available in : /upload/geuvadis/wp4_rnaseq/main_project/analysis_data/ase See the wiki (http://sanabre.net/geuvadis/index.php/Allele_specific_expression) for details of the analysis. Variant annotation info is included in the files; more details again in the wiki (http://sanabre.net/geuvadis/index.php/Variant_annotation). I will be working on the analysis of these data in the next couple of weeks - I'll produce the basic stats and descriptions of ASE, look at the population genetics of ASE, and see how far we can get with mapping of rare regulatory variants. I've also recently developed a pipeline for analyzing allele-specific splicing (ASS :-) ) in a genome-wide manner, but more about that later... have a nice weekend, Tuuli -- Tuuli Lappalainen, PhD Department of Genetic Medicine and Development University of Geneva Medical School CMU / Rue Michel-Servet 1 1211 Geneva 4 Switzerland Tel. +41-(0)22-3795550 tuuli.lappalainen(a)unige.ch