Hello, Here are the minutes of today's TC. The next call will be in one or two weeks, I'll send an email next week. If anyone has analysis approaches/results that they'd like to present, please let me know. On today's call: - We agreed to cancel the third analysis group meeting that we had been putatively planning - Tuuli's unscheduled knee surgery prevents commitment to hosting a meeting anywhere this fall. We'll have a ~2h meeting in Santiago in the morning of Tuesday 30.10. for those who are there. - At the Santiago meeting the RNAseq work package will have a short WP summary presentation and maybe a 30-45 min presentation about the analysis and results (i.e. contents of the paper). Others can also present RNAseq related results; otherwise Tuuli and Manolis will do the presentations - We should schedule a TC for the whole RNAseq group (including the PIs) for late September / early October. - The wiki site will soon move to the CRG server which will change its address but not content. - Discussion on Leiden's miRNA-mRNA correlations that seem to have some bias, as well as some miRNA mapping related questions. miRNA-mRNA correlations will be tested with data that has been normalized for technical variance (Tuuli will provide shortly). - Tuuli presented slides about eQTL methodology - corrections and normalizations of both genotype and expression data, and the main principles and ideas about QTL mapping. Preliminary analysis shows the expected result of transcript quantifications yielding much less eQTLs than exon quantifications. best regards, Tuuli Tuuli Lappalainen, PhD Department of Genetic Medicine and Development University of Geneva Medical School CMU / Rue Michel-Servet 1 1211 Geneva 4 Switzerland Tel. +41-(0)22-3795550 tuuli.lappalainen(a)unige.ch On 8/30/12 2:06 PM, Tuuli Lappalainen wrote: